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Animal Mix (ex2) IgE, Serum

Test ID: MIXEX2
Orderable by Ontario ND

Test

Aliases/Synonyms

BCN001

Method

ImmunoCAP™

Method Description

This is referred to Lab XXX for EORLA clients.
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Platform

Phadia

Report Includes

Animal Mix (ex2) IgE

Specimens

Serum

Clinical Utility

This assay provides a single qualitative (positive/negative) result only. It does not provide information on the amount of IgE specific for any of the component allergens within the mix panel.

In patients suffering from extrinsic asthma, hay fever or atopic eczema, symptoms develop after exposure to specific allergens. This immediate (atopic or anaphylactic) type of allergy is a function of a special type of serum antibodies belonging to the IgE class of immunoglobulins.

Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of symptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

Test Location

ON, CA

Test Version

30-Sep-2019

Specimen

Specimens

Serum

Sample Volume

1 mL

Specimen Comment

Submit enough specimen for number of IgE tests ordered. Each test requires 50 µL and 2 mL is sufficient for 10-12 tests.

Collection & Handling

Handling Information

Store and send frozen.

Additional Information

Refer to the List of Allergens that may also be used as a requisition.

Stability

Refrigerated 3 days
Frozen 6 Months

Test Version

30-Sep-2019

Performance / Interpretation

Method

ImmunoCAP™

Method Description

This is referred to Lab XXX for EORLA clients.
ImmunoCAP™ assays are based on binding of allergen-specific IgE antibodies in serum to allergen (extract or allergen molecule) coupled in excess to a solid phase. Bound IgE is subsequently detected with enzyme-labeled anti-human IgE, where the fluorescence intensity is proportional to the amount of allergen-specific IgE.

Platform

Phadia

Turnaround Time

10 days

Results

Name Units Reference Range Conversion Factor
Animal Mix (ex2), IgE KU/L
  • Negative

This assay detects IgE antibodies to an allergen mix (Cat Dander e1, Dog Dander e5, Guinea pig epithelium e6, Rat e87, Mouse e88). This assay provides a single qualitative result only. It does not provide information on the amount of IgE specific for any of the allergens within the mix.

Interpretation: Clinician must determine clinical significance of specific IgE result after correlation with clinical exam and history. Detectable levels are present in patients with allergic disease and in approx. 15% of asymptomatic healthy persons. Some with classic atopic symptoms may not have detectable levels. Specific IgE may decrease with time and lack of exposure to allergens.

Use caution when interpreting drug, venom and potential anaphylactic allergen results.

Test Location

ON, CA

Test Version

30-Sep-2019

Interface / Setup

Test Version

30-Sep-2019